Genous promotes tissue healing of stent-related injuries in a rapid and controlled manner, unlike drug eluting stents, which indiscriminately inhibit healing reactions using anti-proliferative drugs. Genous captures circulating endothelial progenitor cells (EPCs) to accelerate natural healing. This innovative approach protects against thrombosis and minimizes restenosis. Welcome to the new era of Bio-engineered stents.
Plan for the best – Insure against the worst
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| Bone marrow derived EPCs circulate in the blood stream. |
Genous with anti-hCD34 antibody on the stent surface captures EPCs. |
EPCs mature into endothelial cells, healing the artery with restored endothelium. |
Accelerated Natural Healing
A unique surface priming process prepares a functionalized surface on the bare metal stent. The following bio-chemical reaction results in a biocompatible intermediate matrix. Covalent bonding then achieves antibody attachment. EPCs originate from bone marrow and circulate through the bloodstream. EPCs are captured by antibodies and immobilized on the stent surface. EPC capture, division, and migration continue until a confluent functional endothelial layer is formed between the stent struts.
Stent coating process
The role of endothelium is to:
- Act as a barrier to prevent thrombus formation
- Regulate permeability
- Modulate smooth muscle cell growth
- Produce vasoactive compounds
Unique stent design – innovation that matters
To give the Genous concept an appropriate stent platform, we employ our uniquely designed coronary R stent. Its patented dual helix configuration provides omni-directional flexibility and extremely high radial strength. The stent's cells can be expanded to up to 4.5 mm in diameter, to enable excellent side branch access for bifurcation stenting.
Up to 4.5 mm side branch access
Stent design at an unprecedented level
Technical Drawing (Click on the picture to enlarge)
Product Specifications
| Stent | ||
| Strut dimensions: | 0.0035" (0.09 mm) x 0.0040" (0.10 mm) | |
| Radiopacity: | Moderate | |
| Material: | 316L stainless steel | |
| Side branch access: | 4.5 mm | |
| Foreshortening: | < 1 %* | |
| Recoil: | < 4 %* | |
| Vessel wall coverage: | 17 %* | |
| Radial force (to collapse): | > 25 psi* | |
Balloon Catheter |
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| Proximal shaft: | Hypotube | |
| Nominal pressure: | 9 atm | |
| Rated burst pressure: | 16 atm | |
| Avg. burst pressure: | 27 atm* | |
| Nominal crossing profile: | 0.043" (1.09 mm)* | |
| Catheter tip length: | 5.0 mm | |
| Max. guidewire OD: | 0.014" | |
| Shaft (prox/distal): | 2.2F/2.9F | |
| Guiding catheter compatibility: | 5F (0.057" ID min) for 2.5, 2.75 mm and 6F (0.068" ID min) for 3.0, 3.5, and 4.0 mm |
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* 3.0 mm diameter stent
Ordering Information
 (mm) |
LENGTH (mm) | |||||||
| 9 | 13 | 15 | 18 | 23 | 28 | 33 | ||
| 2.5 | 225-092-5 | 225-132-5 | 225-152-5 | 225-182-5 | 225-232-5 | |||
| 2.75 | 227-092-5 | 227-132-5 | 227-152-5 | 227-182-5 | 227-232-5 | |||
| 3.0 | 230-092-5 | 230-132-5 | 230-152-5 | 230-182-5 | 230-232-5 | 230-282-5 | 230-332-5 | |
| 3.5 | 235-092-5 | 235-132-5 | 235-152-5 | 235-182-5 | 235-232-5 | 235-282-5 | 235-332-5 | |
| 4.0 | 240-092-5 | 240-132-5 | 240-152-5 | 240-182-5 | 240-232-5 | 240-282-5 | 240-332-5 | |