Super User
Genous Stainless Steel
الأحد, 19 نيسان/أبريل 2015 13:28
Genous promotes tissue healing of stent-related injuries in a rapid and controlled manner, unlike drug eluting stents, which indiscriminately inhibit healing reactions using anti-proliferative drugs. Genous captures circulating endothelial progenitor cells (EPCs) to accelerate natural healing. This innovative approach protects against thrombosis and minimizes restenosis. Welcome to the new era of Bio-engineered stents.
Plan for the best – Insure against the worst
 |
||
| Bone marrow derived EPCs circulate in the blood stream. |
Genous with anti-hCD34 antibody on the stent surface captures EPCs. |
EPCs mature into endothelial cells, healing the artery with restored endothelium. |
Accelerated Natural Healing
A unique surface priming process prepares a functionalized surface on the bare metal stent. The following bio-chemical reaction results in a biocompatible intermediate matrix. Covalent bonding then achieves antibody attachment. EPCs originate from bone marrow and circulate through the bloodstream. EPCs are captured by antibodies and immobilized on the stent surface. EPC capture, division, and migration continue until a confluent functional endothelial layer is formed between the stent struts.
Stent coating process
The role of endothelium is to:
- Act as a barrier to prevent thrombus formation
- Regulate permeability
- Modulate smooth muscle cell growth
- Produce vasoactive compounds
Unique stent design – innovation that matters
To give the Genous concept an appropriate stent platform, we employ our uniquely designed coronary R stent. Its patented dual helix configuration provides omni-directional flexibility and extremely high radial strength. The stent's cells can be expanded to up to 4.5 mm in diameter, to enable excellent side branch access for bifurcation stenting.
Up to 4.5 mm side branch access
Stent design at an unprecedented level
Technical Drawing (Click on the picture to enlarge)
Product Specifications
| Stent | ||
| Strut dimensions: | 0.0035" (0.09 mm) x 0.0040" (0.10 mm) | |
| Radiopacity: | Moderate | |
| Material: | 316L stainless steel | |
| Side branch access: | 4.5 mm | |
| Foreshortening: | < 1 %* | |
| Recoil: | < 4 %* | |
| Vessel wall coverage: | 17 %* | |
| Radial force (to collapse): | > 25 psi* | |
Balloon Catheter |
||
| Proximal shaft: | Hypotube | |
| Nominal pressure: | 9 atm | |
| Rated burst pressure: | 16 atm | |
| Avg. burst pressure: | 27 atm* | |
| Nominal crossing profile: | 0.043" (1.09 mm)* | |
| Catheter tip length: | 5.0 mm | |
| Max. guidewire OD: | 0.014" | |
| Shaft (prox/distal): | 2.2F/2.9F | |
| Guiding catheter compatibility: | 5F (0.057" ID min) for 2.5, 2.75 mm and 6F (0.068" ID min) for 3.0, 3.5, and 4.0 mm |
|
* 3.0 mm diameter stent
Ordering Information
 (mm) |
LENGTH (mm) | |||||||
| 9 | 13 | 15 | 18 | 23 | 28 | 33 | ||
| 2.5 | 225-092-5 | 225-132-5 | 225-152-5 | 225-182-5 | 225-232-5 | |||
| 2.75 | 227-092-5 | 227-132-5 | 227-152-5 | 227-182-5 | 227-232-5 | |||
| 3.0 | 230-092-5 | 230-132-5 | 230-152-5 | 230-182-5 | 230-232-5 | 230-282-5 | 230-332-5 | |
| 3.5 | 235-092-5 | 235-132-5 | 235-152-5 | 235-182-5 | 235-232-5 | 235-282-5 | 235-332-5 | |
| 4.0 | 240-092-5 | 240-132-5 | 240-152-5 | 240-182-5 | 240-232-5 | 240-282-5 | 240-332-5 | |
Genous CoCr
الأحد, 19 نيسان/أبريل 2015 13:27
Plan for the best – Insure against the worst
|
||
Bone marrow derived EPCs
|
Genous with anti-hCD34
|
EPCs mature into endothelial cells, healing the artery with restored endothelium. |
Design Matters
The Genous Bio-engineered Cobalt Chromium Stent has a unique dual helix design that provides natural conformability and tremendous radial strength without compromising its extreme flexibility.
Squared Ends
– for lesion coverage and minimal foreshortening
Dual Helix Backbone
– for flexibility, radial strength and natural conformability
Sinusoidal Rings
– for scaffolding, coverage, and support
Unsurpassed Sidebranchability
Up to 4.5 mm side branch access for effective bifurcation stenting and for maintaining patency of side branches.
Material Matters
The Genous CoCr stent is made from the L605 cobalt chromium alloy, which has no molybdenum and less nickel than 316L stainless steel and MP35N cobalt chromium alloy. Some patients are allergic to both nickel and molybdenum and can develop restenosis as a result.1
1. Koster, R, et al., The Lancet, 2000, 356:1895-7. Nickel and Molybdenum Contact Allergies in Patients With Coronary In-stent Restenosis.
Thinner is Better
Thinner stent struts are better, as long as radial force is not compromised. Thinner metal results in a lower profile, greater flexibility, and reduced restenosis.2
2. Pache, J, et al., Journal of the American College of Cardiology, April, 2003, 16;41(8):1289-92. Intracoronary stenting and angiographic results: strut thickness effect on restenosis outcome (ISAR-STEREO-2) trial.
Technical Drawing (Click on the picture to enlarge)
Product Specifications
| Stent | ||
| Strut dimensions: | 0.0034" (0.09 mm, width) x 0.0032" (0.08 mm, thickness) | |
| Radiopacity: | Moderate | |
| Material: | L605 cobalt chromium alloy | |
| Side branch access: | 4.5 mm | |
| Foreshortening: | < 2 %* | |
| Recoil: | < 5 %* | |
| Vessel wall coverage: | 14 %* | |
| Radial force (to 50% lumen collapse): | 26 Psi* | |
Balloon Catheter |
||
| Proximal shaft: | Hypotube | |
| Nominal pressure: | 9 atm | |
| Rated burst pressure: | 16 atm | |
| Avg. burst pressure: | > 28 atm | |
| Nominal crossing profile: | 0.038" (0.97 mm)* | |
| Catheter tip length: | 4.25 mm | |
| Max. guidewire OD: | 0.014" | |
| Shaft (prox/distal): | 2.3F/2.9F | |
| Guiding catheter compatibility: | 5F (0.056" ID min) | |
*3.00 mm diameter stent
Ordering Information
| (mm) |
LENGTH (mm) | |||||||
| 9 | 13 | 15 | 18 | 23 | 28 | 33 | ||
| 2.5 | 225-092-7 | 225-132-7 | 225-152-7 | 225-182-7 | 225-232-7 | |||
| 2.75 | 227-092-7 | 227-132-7 | 227-152-7 | 227-182-7 | 227-232-7 | |||
| 3.0 | 230-092-7 | 230-132-7 | 230-152-7 | 230-182-7 | 230-232-7 | 230-282-7 | 230-332-7 | |
| 3.5 | 235-092-7 | 235-132-7 | 235-152-7 | 235-182-7 | 235-232-7 | 235-282-7 | 235-332-7 | |
| 4.0 | 240-092-7 | 240-132-7 | 240-152-7 | 240-182-7 | 240-232-7 | 240-282-7 | 240-332-7 | |
Orbusneich
الأحد, 19 نيسان/أبريل 2015 13:22
The Genous Bio-engineered surface features antibodies immobilized on the stent that capture circulating endothelial progenitor cells (EPCs), which in turn rapidly form an endothelial layer over and between the stent struts. This protects against thrombus and minimizes restenosis.
Welcome To Our Website
الأحد, 19 نيسان/أبريل 2015 11:17Nebras aims to be the market leader in the field of Biomedical Equipment and Medical Supplies to supply healthcare organizations with latest innovations, best quality and value added products to Jordan and Middle East's communities and to share in developing the healthcare industry in the Middle East. Nebras works constantly to improve customer satisfaction, and employee opportunity and shareholder value.
Partnership
الخميس, 16 نيسان/أبريل 2015 07:09For supplying of pharmaceuticals from different manufacturers in Jordan
For supplying pharmaco- herbal products
Company Profile
About Nebras
Peptest
Professional Staff
We have a proffessional in marketing and sales and distribution.
